FM6 320
192
Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression PatternsB. De Laere, P.-J. van Dam, T. Whitington, M. Mayrhofer, E.H. Diaz, G. Van den Eynden,
J. Vandebroek, J. Del-Favero, S. Van Laere, L. Dirix, H. Grönberg, J. Lindberg
Structural variation is prevalent in the androgen receptor (AR), suggesting a
connection to the expression of splice variants. Comprehensive AR profiling, which is
possible to perform on liquid biopsies, is necessary to reveal the complexity of the
AR signalling processes underpinning resistance to endocrine treatment.
201
Investigating Genomic Aberrations of the Androgen Receptor: Moving Closer to More Precise Prostate Cancer Care?J. Mateo, A. Sharp, J.S. de Bono
205
Minimally Invasive, Laparoscopic, and Robotic-assisted Techniques Versus Open Techniques for Kidney Transplant Recipients: A Systematic ReviewS. Wagenaar, J.H. Nederhoed, A.W.J. Hoksbergen, H.J. Bonjer, W. Wisselink, G.H. van Ramshorst
The general level of evidence of articles included in this systematic review was low.
Minimally invasive techniques showed promising results with regard to
complications and recovery. For open surgery, the smallest possible Gibson incision
appeared to yield favorable results.
218
Is Robotic Kidney Transplant the Near Future?A. Alcaraz, L. Peri, L. Izquierdo, M. Musquera
220
Tract Sizes in Miniaturized Percutaneous Nephrolithotomy: A Systematic Review from the European Association of Urology Urolithiasis Guidelines PanelY. Ruhayel, A. Tepeler, S. Dabestani, S. MacLennan, A. Petrˇík, K. Sarica, C. Seitz, A. Skolarikos,
M. Straub, C. Türk, Y. Yuan, T. Knoll
Percutaneous nephrolithotomy (PNL) using smaller tract sizes (<22 Fr, mini-PNL) for
removal of renal calculi appears to be as efficacious and safe as standard PNL.
However, the studies are heterogeneous and generally small, so well-designed and
sufficiently powered randomized controlled trials are warranted.
236
Miniaturized Percutaneous Nephrolithotomy: A Decade of Paradigm Shift in Percutaneous Renal AccessM.R. Desai, A.P. Ganpule
238
Low-risk Prostate Cancer: Identification, Management, and OutcomesM. Moschini, P.R. Carroll, S.E. Eggener, J.I. Epstein, M. Graefen, R. Montironi, C. Parker
The incidence of low-risk prostate cancer has increased in recent years; however,
only a few patients die from the disease while no survival benefit has been shown
with local treatment. Biomarkers and imaging may help to identify patients with
clinically significant disease.
250
What Is the Negative Predictive Value of Multiparametric Magnetic Resonance Imaging in Excluding Prostate Cancer at Biopsy? A Systematic Review and Meta-analysis from the European Association of Urology Prostate Cancer Guidelines PanelP.C. Moldovan, T. Van den Broeck, R. Sylvester, L. Marconi, J. Bellmunt, R.C.N. van den Bergh,
M. Bolla, E. Briers, M.G. Cumberbatch, N. Fossati, T. Gross, A.M. Henry, S. Joniau,
T.H. van der Kwast, V.B. Matveev, H.G. van der Poel, M. De Santis, I.G. Schoots, T. Wiegel,
C.Y. Yuan, P. Cornford, N. Mottet, T.B. Lam, O. Rouvière
Prostate cancer prevalence was highly variable among patients referred to
prebiopsy multiparametric magnetic resonance imaging (mpMRI). As the negative
predictive value depends on the prevalence, patients submitted to mpMRI must be
reliably risk stratified before defining who may omit prostate biopsy when mpMRI is
negative.
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Renal Disease
Stone Disease
Review
Prostate Cancer
Guidelines