Table of Contents Table of Contents
Previous Page  219 320 Next Page
Information
Show Menu
Previous Page 219 320 Next Page
Page Background

it is the technique most commonly used worldwide. Once

its feasibility and safety were proven, the world experience

was collected, including a few small RCTs that showed equal

efficacy and less invasion, and the approach became the

standard of care.

After many years of experimental work on LKT, including

our own, and several attempts in a small number of

patients, only one group was able to establish a stable and

durable program

[7]

. These authors recognised the extreme

difficulty of the technique and recorded loss of two grafts in

their early experience. Renewed enthusiasm emerged with

the arrival of robotics. Nowadays, LKT has been replaced by

RKT. The use of articulated instruments, together with

three-dimensional vision (already available in laparoscopy),

potentially allows a reduction in warm ischaemia time

(WIT) by reducing the revascularisation suture time.

The world experience is actually recent. It begun in 2009,

since

[4_TD$DIFF]

then more than 500 RKT procedures have been

performed. However, approximately 70% of the world

experience is concentrated in two Indian institutions, the

Mehta Institute (Ahmedabad) and Medanta Hospital

(Gurgao)

[8]

, with the support of the Vattikuti Urology

Institute (Detroit, MI, USA)

[9] .

Several institutions in

Europe have implemented the procedure, mainly using the

Medanta technique, and a European register (ERUS) has

been created that already includes 100 patients who have

received a transplant.

From the European experience, including our own

department, it can be said that RKT is a technique that is

already systematised, is reproducible, and has yielded

equivalent results to OKT in terms of graft and patient

survival. As a result of the longer WIT and the probably

negative effect of pneumoperitoneum, slower recovery of

renal function can be observed, but there are no differences

after 3 mo. Cooling of the kidney during the procedure is

probably the most important unsolved problem that

hampers speed in revascularising the kidney, with all the

associated complications in terms of stress and quality of

the sutures.

RKT allows early recovery, especially in obese patients,

and better cosmesis, mainly because of the smaller incision

used exclusively to introduce the kidney into the abdominal

cavity. This incision can be avoided in some women by

using a transvaginal approach, a route for which there is

wide experience for kidney retrieval

[10]

.

Conflicts of interest:

The authors have nothing to disclose.

References

[1]

Wagenaar S, Nederhoed JH, Hoksbergen AWJ, Bonjer HJ, Wisselink W, van Ramshorst GH. Minimally invasive, laparoscopic, and ro- botic-assisted techniques versus open techniques for kidney trans- plant recipients: a systematic review. Eur Urol 2017;72:205–17

.

[2]

Aminsharifi A, Salehipoor M, Arasteh H. Systemic immunologic and inflammatory response after laparoscopic versus open nephrec- tomy: a prospective cohort trial. J Endourol 2012;26:1231–6

.

[3]

Nanidis TG, Antcliffe D, Kokkinos C, et al. Laparoscopic versus open live donor nephrectomy in renal transplantation: a meta-analysis. Ann Surg 2008;247:58–70.

[4]

Modi P, Rizvi J, Sharma V, et al. Retroperitoneoscopic living donor nephrectomy and laparoscopic kidney transplantation: experience of first 72 cases. Transplantation 2013;94:186

.

[5]

Ratner LE, Ciseck LJ, Moore RG, Cigarroa FG, Kaulfman HS, Kavoussi LR. Laparoscopic live donor nephrectomy. Transplantation 1995; 60:1047

.

[6]

Ka¨lble T, Lucan M, Nicita G, et al. EAU guidelines on renal trans- plantation. Eur Urol 2005;47:156–66.

[7]

Modi P, Rizvi J, Pal B, et al. Laparoscopic kidney transplantation: an initial experience. Am J Transplant 2011;11:1320–4

.

[8]

Sood A, Ghosh P, Jeong W, et al. Minimally invasive kidney trans- plantation: perioperative considerations and key 6-month out- comes. Transplantation 2015;99:316–23

.

[9]

Menon M, Sood A, Bhandari M, et al. Robotic kidney transplantation with regional hypothermia: a step-by-step description of the Vat- tikuti Urology Institute-Medanta Technique (IDEAL Phase 2a). Eur Urol 2014;65:991–1000

.

[10]

Peri L, Musquera M, Vilaseca A, et al. Perioperative outcome and female sexual function after laparoscopic transvaginal NOTES- assisted nephrectomy. World J Urol 2015;33:2009–14.

E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 2 1 8 – 2 1 9

219