212 320
Table 4 – Reported outcomes per study—baseline characteristics
Author
Surgical
technique
Patients
(
n
)
Subgroup
(
n
)
Gender
(m/f)
Age (yr)
Weight
(kg)
BMI
(kg/m
2
[1_TD$DIFF]
)
Living/cadaveric
donor
Operative
time (min)
Cold
ischemic
time (h)
Warm
ischemic
time (min)
Gibson incision
Nanni (2005)
[7]
GIBI
100
50 34/16 45 9
74 13 NR
NR
NR
NR
NR
Oberholzer (2013)
[14]
GIBI
56
28 11/17 49.8 10.8
NR 38.1 5.4
*26/2
NR
2.0 4.5
49.2 25.2
Modi (2013)
[13]
GIBI
217
145 126/19 35.9 (11–62)
NR 22.3 (16.9–30.5)
145/–
175.7 [75–265]
0.79 (0.23–1.6)
*30.3 (19–53)
*Hockey-stick incision
Nanni (2005)
[7]
HSI
100
50 35/15 46 12
72 14 NR
NR
NR
NR
NR
Filocamo (2007)
[34] aHSI
400
267 174/93 Group 1: 47 (15–63),
group 2: 45 (18–60),
group 3: 55 (17–71)
aNR Combined: 27,4 3.3
a NR
NR
NR
NR
Malinka (2013)
[33]
HSI
66
33 20/13 51.4 11.6
NR 26.3 4.4
10/23
188.7 55.9
7.75 5.77
32.5 8.6
Kishore (2014)
[9]
HSI
50
25 20/5 34 11
NR 21 3.1
NR
NR
NR
NR
Conventional open
kidney transplantation
bØyen (2006)
[35]
COKT
42
21 17/4 55 (18–78)
NR 24.4 (18–33)
5/16
187 (130–270)
*14.3 (7–22)
NR
Mun (2007)
[18]
COKT
40
20 NR
40.1 (32–52)
NR 35.5 (26.9–38.2)
*20/–
159 (129–205)
NR
NR
Kacar (2013)
[37]
COKT
86
43 28/15 42.7
NR 25.9
41/2
153.5
1.06
NR
Brockschmidt (2014)
[20] COKT
22
11 NR
41.1 12.9 (21–64)
NR 24.2 3.5 (19.8–30.5) 11/–
111 16 (90–145)
1.28 0.48
(0.67–2.22)
*AT: 26 5.4 (17–38)
cModi (2015)
[22]
COKT
36
8 –/8
37.5 17.3
NR 20.7 2.12
8/–
179.4 36.88
*0.83 0.26
*36.48 6.4
*Kim (2016)
[21]
COKT
452
435 271/164 43.6 11.0
NR 22.98 3.76
435/0
NR
NR
NR
Minimally invasive open
kidney transplantation
Øyen (2006)
[35]
MIKT
42
21 18/3 56 (32–75)
NR 25.7 (21–32)
5/16
118 (95–140)
*13.4 (7–21)
NR
Filocamo (2007)
[34]
MLI
400
133 84/49 54 (18–60)
NR 28.2 2.0
NR
NR
NR
NR
Mun (2007)
[18]
MIVAKT
40
20 NR
36.8 (18–45)
NR 29.7 (25.6–34.1)
*20/–
178 (156–210)
NR
NR
Park (2008)
[36]
MSI
5
5 –/5
24 3.6
NR 17.5 2.5
NR
Not significant, NS
NR
NR
Brockschmidt (2012)
[19] MAKT
10
10 NR
47 14.7
NR 25 2.02 (23–30)
NR
126.2 27.5 (90–165) 14.4 6.4
(1.8–24)
AT: 27.7 8.4 (19–45)
cKacar (2013)
[37]
MIKT
86
43 32/11 39.5
NR 23.8
42/1
164.2
1.01
NR
Malinka (2013)
[33]
STI
66
33 26/7 54.5 12.6
NR 25.2 4.6
7/26
194.4 50.5
7.97 4.33
34.6 12.3
Brockschmidt (2014)
[20] MAKT
22
11 NR
40.1 11.7 (25–61)
NR 24.8 5.6 (19.5–32.4) 11/–
121 11.9 (102–141) 1.9 0.37 (1–2.33)
* AT: 27 6.2 (19–37)
cKishore (2014)
[9]
MFI
50
25 20/5 38 9
NR 20 2.9
NR
NR
NR
NR
Kim (2016)
[21]
MSI
452
17 0/17 26.5 9.3
NR 18.72 2.47
17/0
NS
NR
NR
Laparoscopic kidney
transplantation
Modi (2013)
[13]
LKT (suprapubic)
217
72 63/9 34.4 (16–64)
NR 20.5 (14.3–33)
72/–
223.8 (160–325)
1.77 (0.43–3.82)
*60.3 (47–90)
*Modi (2015)
[22]
LKT (suprapubic)
36
20 –/20 33.90 11.08
NR 20.41 5.09
20/–
224.75 31.89
1.57 0.73
67.15 17.73
Modi (2015)
[22]
LKT (transvaginal)
36
8 –/8
35.3 8.24
NR 19.8 4.24
8/–
242.1 31.9
*1.63 0.81
*62.90 9.93
*Robotic-assisted kidney
transplantation
Oberholzer (2013)
[14]
RAKT
56
23 13/15 47.9 10.7
NR 42.6 7.8
* [6_TD$DIFF]26/2
NR
2.8 3.6
47.7 7.8
Menon (2014)
[15]
RAKT
25
25 17/8 37.2 15.8 (16–67)
NR 24.1 4.8 (17.4–38.6) 25/–
214.1 39.8 (156–293) NR
2.4 1.1 (1.5–6.0),
rewarming time
with ice slush
46.6 9.3 (27–66),
total rewarming
time 75.3 19.2
(50.7–142.5)
cTsai (2014)
[16]
RAKT
10
10 5/5
43.6 13.8 (21–61)
NR 22.8 3.5 (18.9–28.2) 6/4
257.8 52.7 (187–341) NR
NR
Sood (2015)
[17]
RAKT
54
54 41/13 37.3 13.5 (16–67)
NR 23.5 4.8 (15.5–42.3) 54/–
201.1 33.8 (156–293) 0.46 0.26
(0.17–1.5)
In donor
2.3 0.8 (1.3–6.0),
rewarming
time including
ice slush
time 42.9 7.6
(27–66)
cTugcu (2016)
[30]
RAKT
15
15 7/8
37.4 10.8
NR 22.6 3.4
15/–
300.3 104.2
NR
1.9 0.5,
rewarming time
including ice slush
time 73.3 30.7
cNR = not reported; NS = not specified; AT = anastomosis time; GIBI = Gibson incision; HSI = hockey-stick incision; MLI = midline incision; COKT = conventional open kidney transplantation; MIKT = minimally invasive
kidney transplantation; MIVAKT = minimally invasive video-assisted kidney transplantation; MSI = modified skin incision technique; MAKT = minimal-access kidney transplantation; MFI = modified Pfannenstiel incision;
LKT = laparoscopic kidney transplantation; RAKT = robotic-assisted kidney transplantation; KTx = kidney transplantation surgery; STI = short transverse incision; = standard deviation; (–) = range.
*
Significant result (
p
<
0.05).
a
Three subgroups: group 1: 1991–1997, operated by surgeons (
n
= 65); group 2: 1991–1997, operated by urologists (
n
= 67); group 3: 1997–2005, operated by surgeons (
n
= 135), when possible results were combined.
b
Conventional open kidney transplantation, not specified which open technique, either being KTx with GIBI or KTx with HSI.
c
Different definitions of warm ischemic time were used. When not reported as anastomosis time + warm ischemic time during nephrectomy, time was reported separately.
E U R O P E A N U R O L O G Y 7 2 ( 2 0 1 7 ) 2 0 5 – 2 1 7
212